SM-276001 NEW
Price | $58 | $142 | $213 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: SM-276001 | CAS No.: 473930-22-2 |
Purity: 99.37% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | SM-276001 |
Description | SM-276001 is a potent, selective agonist of TLR7 and an orally active interferon (IFN) inducer. |
In vitro | SM-276001 (1 nM-10 μM) activates NF-κB in a dose-dependent manner via human TLR7 [2]. |
In vivo | Oral administration of 0.1 mg/kg SM-276001 in mice shows potent IFN-inducing activity [1]. Twice weekly oral administration of SM-276001 at a dose of 3 mg/kg significantly reduced disease burden in mice bearing either Renca or CT26 tumors.[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (305.46 mM) |
Keywords | Toll-like Receptor (TLR) | TLR7 | SM-276001 | SM276001 | SM 276001 | Interferon-α/β receptor | Interferon-alpha/beta receptor | interferon | Inhibitor | inhibit | immune | IFNAR | IFN | antitumor |
Inhibitors Related | Bismuth Subsalicylate | Ibuprofen | Acetaminophen | Salicylamide | Hydroxychloroquine | Diclofenac sodium | Diclofenac Potassium | Chloranil | Paradol | Salicylic acid | Glafenine | Revaprazan hydrochloride |
Related Compound Libraries | Reprogramming Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | HIF-1 Signaling Pathway Compound Library | Pyroptosis Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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