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Postion:Product Catalog >SM-276001
SM-276001
  • SM-276001

SM-276001 NEW

Price $58 $142 $213
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SM-276001 CAS No.: 473930-22-2
Purity: 99.37% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSM-276001
DescriptionSM-276001 is a potent, selective agonist of TLR7 and an orally active interferon (IFN) inducer.
In vitroSM-276001 (1 nM-10 μM) activates NF-κB in a dose-dependent manner via human TLR7 [2].
In vivoOral administration of 0.1 mg/kg SM-276001 in mice shows potent IFN-inducing activity [1]. Twice weekly oral administration of SM-276001 at a dose of 3 mg/kg significantly reduced disease burden in mice bearing either Renca or CT26 tumors.[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (305.46 mM)
KeywordsToll-like Receptor (TLR) | TLR7 | SM-276001 | SM276001 | SM 276001 | Interferon-α/β receptor | Interferon-alpha/beta receptor | interferon | Inhibitor | inhibit | immune | IFNAR | IFN | antitumor
Inhibitors RelatedBismuth Subsalicylate | Ibuprofen | Acetaminophen | Salicylamide | Hydroxychloroquine | Diclofenac sodium | Diclofenac Potassium | Chloranil | Paradol | Salicylic acid | Glafenine | Revaprazan hydrochloride
Related Compound LibrariesReprogramming Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | HIF-1 Signaling Pathway Compound Library | Pyroptosis Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$119.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
$1820.00/25mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-23
$0.00/1g
VIP4Y
XIAMEN SINOPEG BIOTECH CO., LTD.
2024-11-25
$58.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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