Sitagliptin NEW
Price | Get Latest Price | ||
Package | 10g | 100g | 1000g |
Min. Order: | 10g |
Supply Ability: | 10000 |
Update Time: | 2024-11-01 |
Product Details
Product Name: Sitagliptin | CAS No.: 486460-32-6 |
Min. Order: 10g | Purity: 99% HPLC |
Supply Ability: 10000 | Release date: 2024/11/01 |
Description: Sitagliptin, also known as MK-0431, is a potent inhibitor of DPP4 with an Ic50 of 19 nM in Caco-2 cell extractsSitagliptin is believed to exert its actions in patients with type 2 diabetes melitus by slowing the inactivation of incretin hormones. By increasing and prolonging active incretin levels, sitagliptin increases insulin release and decreases qlucagon levels inthe circulation in a glucose-dependent manner. Sitagliptin demonstrates selectivity for Dpp-4 and does not inhibit DPp-8 orDPp-9 activity in vitro at concentrations approximating those from therapeutic doses.
Synonym: Sitagliptin; LEZ 763; LEZ-763; LEZ763; MK0431; MK 0431; MK-0431;IUPAC/chemical Name: (R)-3-amino-1-(3-(trifluoromethyl)-5,6- dihydro-[1,2,4]triazolof4,3-alpyrazin-7(8H)-yl)-4-(2,4, 5-trifluo
rophenyl)butan-1-oneInchi
Key:MFFMDFFZMYYVKSSECBINFHSA-NInchi code: Inchl=1S/C16H15F6N50/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
SMILES Code: FC(C1=NN=C2CN(C(C[C@H](N)CC3=CC(F)=C(F)C=C3F)=0)CCN21)(F)
FAppearance: Solid powder
Purity:>98% (or refer to the Certificate of Analysis)
Shipping Condition: shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMso
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Company Profile Introduction
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$10.00/25kg |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-01 | |
$36.00/50mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-31 | |
$36.00/50mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-10-31 | |
$1000.00/1kg |
VIP3Y
|
Hebei Dangtong Import and export Co LTD
|
2024-09-13 | |
$0.00/1g |
VIP1Y
|
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
|
2024-09-05 | |
$100.70/1KG |
VIP4Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-22 | |
$1000.00/1kg |
VIP1Y
|
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
|
2024-08-12 | |
$0.00/1Kg/Bag |
VIP4Y
|
Sinoway Industrial co., ltd.
|
2024-06-27 | |
$18.00/10kg |
VIP1Y
|
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
|
2024-05-10 | |
$100.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-04-24 |
- Since: 2022-10-14
- Address: Room 530, 5F, building 10, Xintiandi business center, Gongshu District, Hangzhou City, Zhejiang Prov
+86-18882027439
sales2@runyanpharma.com