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Postion:Product Catalog >SBC-115337
SBC-115337
  • SBC-115337

SBC-115337 NEW

Price $53 $148 $227
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SBC-115337 CAS No.: 423148-46-3
Purity: 99.41% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSBC-115337
DescriptionSBC-115337 is a PCSK9 inhibitor.
In vitroThe potent compound (SBC-115,337) demonstrated an IC50 of 0.6 μM in an in vitro ELISA assay for monitoring PCSK9 binding to recombinant LDLR. All tested compounds did not affect PCSK9 synthesis, processing, or secretion. At 1.2 μM, SBC-115,337 induced more than tenfold upregulation of LDLR in HepG2 cells, increased uptake of fluorescently labeled DiI-LDL, and lowered LDL-c levels in mice on a high-fat diet.[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : <1 mg/mL (insoluble or slightly soluble), Sonication and heating to 60℃ are recommended.
KeywordsSBC115337 | Serine endopeptidases | benzofuran | LDLR | Threonine proteases | SBC 115337 | SBC-115337 | Ser/Thr Protease | inhibit | Inhibitor | recombinant | potent | DiI-LDL | Serine proteases | HepG2
Inhibitors RelatedNafamostat mesylate | Piceatannol | CID755673 | SBC-115076 | Fasudil hydrochloride | Camostat mesylate | SRPIN340 | HA-1004 | FOY 251 | BMT-124110 Formate | Benzamidine hydrochloride | Cetraxate hydrochloride
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Protease Inhibitor Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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