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Postion:Product Catalog >Saroglitazar Magnesium
Saroglitazar Magnesium
  • Saroglitazar Magnesium

Saroglitazar Magnesium NEW

Price $88 $232 $358
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Saroglitazar Magnesium CAS No.: 1639792-20-3
Purity: 98.1% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSaroglitazar Magnesium
DescriptionSaroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARα (EC50 0.65pM) and moderate activation against PPARγ (EC50 3 nM).
In vivoIn db/db mice, Saroglitazar (0.01-3 mg/kg per day, orally) treatment with 12-day causes dose-dependent reductions in serum triglycerides (TG), free fatty acids (FFA), and glucose. The ED50 for these effects is found to be 0.05, 0.19, and 0.19 mg/kg, respectively with highly significant (91%) reduction in serum insulin and AUC-glucose following oral glucose administration (59%) at 1 mg/kg dose.in Wistar rats and marmosets A 90-day repeated dose comparative study confirms efficacy (TG lowering) potential of Saroglitazar and has indicated low risk of PPAR-associated side effects in humans. Based on efficacy and safety profile, Saroglitazar appears to have good potential as novel therapeutic agent for treatment of dyslipidemia and diabetes[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 112.5 mg/mL (124.8 mM), Sonication is recommended.
KeywordsSaroglitazar Magnesium
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Anti-Diabetic Compound Library | Anti-Obesity Compound Library | Drug Repurposing Compound Library | Mitochondria-Targeted Compound Library | Lipid Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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