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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>(S)-1-Boc-3-hydroxypiperidine
(S)-1-Boc-3-hydroxypiperidine
  • (S)-1-Boc-3-hydroxypiperidine

(S)-1-Boc-3-hydroxypiperidine

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2023-03-12

Product Details

Product Name: (S)-1-Boc-3-hydroxypiperidine CAS No.: 143900-44-1
Min. Order: 1kg Purity: 98.0%min
Supply Ability: 100kg Release date: 2023/03/12
Package: foil bag; fibber/steel drum; glass bottle etc. Shipment: professional agent on courier, air, sea
Contact: marsha@lychems.cn
(S)-1-Boc-3-hydroxypiperidine Basic information
Uses
Product Name:(S)-1-Boc-3-hydroxypiperidine
Synonyms:(S)-3-HYDROXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(S)-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE;(S)-1-BOC-3-HYDROXYPIPERIDINE;(S)-1-BOC-3-PIPERIDINOL;(S)-N-(TERT-BUTOXYCARBONYL)-3-HYDROXYPIPERIDINE HYDROCHLORIDE;(S)-N-BOC-3-HYDROXY PIPERIDINE;(S)-TERT BUTYL-3-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-PIPERIDINECARBOXYLIC ACID, 3-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, (3S)-
CAS:143900-44-1
MF:C10H19NO3
MW:201.26
(S)-1-Boc-3-hydroxypiperidine Chemical Properties
Melting point 34-40 °C
Boiling point 292.3±33.0 °C(Predicted)
density 1.107±0.06 g/cm3(Predicted)
Fp 110 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Soluble in methanol.
pka14.74±0.20(Predicted)
form Powder or Crystalline Powder
color White to tan
optical activity[α]22/D +10.0°, c = 1 in chloroform
InChIKeyUIJXHKXIOCDSEB-QMMMGPOBSA-N
CAS DataBase Reference143900-44-1(CAS DataBase Reference)
Uses(S)-1-Boc-3-hydroxypiperidine is an important chiral intermediate for the synthesis of ibrutinib, an anticancer drug targeting B-cell malignancies. Synthesis of pharmaceutical intermediates including ibrutinib, the API of the newly approved drug Imbruvica, for the treatment of lymphoma.
UsesA piperidine derivative with an amine protecting group, (S)-1-Boc-3-hydroxypiperidine can be used in the preparation of biologically active compounds such as antagonists of the human P2X7 receptor and selective irreversible inhibitors for bruton's tyrosine kinase.
Uses(S)-1-Boc-3-hydroxypiperidine is used as pharmaceutical intermediate.


Company Profile Introduction

LY Global Chemicals Co Ltd.. is a limited liability company specialized in technical research and development, production, development and trade of chemical products. Mainly engaged in the customization and sales of pharmaceutical intermediates, electronic materials, cosmetics raw materials and other fine chemicals. We have many years of export experience, and our customers are all over many countries. Our products are of good quality, competitive price, stable supply, and customers are very satisfied

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