成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >RS102895 hydrochloride
RS102895 hydrochloride
  • RS102895 hydrochloride

RS102895 hydrochloride NEW

Price $40 $60 $90
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: RS102895 hydrochloride CAS No.: 1173022-16-6
Purity: 98.95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRS102895 hydrochloride
DescriptionRS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
In vitroRS102895 hydrochloride is a potent antagonist of CCR2(IC50 : 360 nM). RS102895 inhibits human α1a and α1d receptors, rat brain cortex 5HT1a receptor in cells with IC50s of 130, 320, 470 nM, respectively. RS102895 suppresses wild type and D284N mutant MCP-1 receptor with IC50 of 550 nM and 568 nM, respectively. RS102895 less potently inhibits D284A MCP-1 receptor with IC50 of 1892 nM. RS102895 ameliorates the increased extracellular matrix (ECM) protein expression by inhibition of CCR2 at 10 μM, and obviously blocks fibronectin and type IV collagen protein expression in high glucose (HG)-stimulated mesangial cells (MCs) at 1 or 10 μM. RS102895 (10 μM) also abrogates the increased TGF-1 levels in MCs treated with MCP-1[2].
In vivoProgressive decrease in pain threshold in rats with bone cancer pain (BCP) at day 3-9 after surgery via intrathecal injection caused by RS102895 (3 g/L), but the pain threshold increases after 12 days. RS102895 also potently reverses the pattern of NR2B, nNOS, and SIGIRR expression in spinal cord[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 28 mg/mL (65.60 mM)
KeywordsCCR | RS-102895 hydrochloride | CC chemokine receptor | Inhibitor | RS-102895 | inhibit | RS 102895 Hydrochloride | RS102895 hydrochloride | RS-102895 Hydrochloride | RS 102895 | RS102895 Hydrochloride | RS102895
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Pirfenidone | Trazodone hydrochloride
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Serotonin Receptor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$40.00/2mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
$0.00/1kg
VIP3Y
Henan Aochuang Chemical Co.,Ltd.
2022-09-07
$1.00/1KG
VIP6Y
Career Henan Chemical Co
2020-02-18
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY