It is used to treat acute and chronic schizophrenia and various other psychotic states with clearly positive symptoms (e.g., hallucinations, fantasies, disorganization of thought, hostility, suspicion) and clearly negative symptoms (e.g., lethargy, emotional and social apathy, low speech). It may also reduce the emotional symptoms associated with schizophrenia (e.g., depression, guilt, anxiety). For patients who are effective in the acute phase of treatment, Vistone can continue to exert its clinical efficacy during the maintenance phase of treatment.

Advantages and Side Effects Advantages of risperidone:

(1) It is not only effective for positive symptoms, but also effective for negative symptoms, and can also improve the cognitive impairment of patients, thereby improving the condition of patients as a whole. (2) The adverse reactions of drugs are light, and there are fewer extrapyramidal side effects. (3) Dose adjustment is easy, for most patients, the dose is 2 ~ 6mg/d, can produce curative effect. (4) Risperidone can produce a better effect on some patients with poor or intolerable treatment effect of conventional antipsychotic drugs. (5) Patients' compliance during medication was greatly increased. (6) Foreign studies have shown that risperidone can reduce the cost of patients and reduce the overall expenditure of patients, which is more in line with the principles of health economics.

Side effects of risperidone: The common adverse reactions of risperidone are: insomnia, anxiety, agitation, headache; Less common adverse reactions include drowsiness, fatigue, dizziness, decreased concentration, constipation, dyspepsia, nausea, vomiting, abdominal pain, blurred vision, abnormal penile erection, erectile difficulty, weak ejaculation, apathy, urinary incontinence, rhinitis, rash, and other allergic reactions. Risperidone can cause extrapyramidal side effects, tremors, rigidity, salivation, bradykinesia, asthenia, acute dystonia, and occasionally postural hypotension, lactation, gynecomastia, menstrual disorders, and amenorrhea. Risperidone is also associated with weight gain, edema, and increased liver enzymes.

Drug interaction

1 This product can antagonize the effect of levodopa and other dopamine agonists. 

2 Amidazine and other liver enzyme inducers will reduce the plasma concentration of the active ingredient of this product. Once the use of amidazine or other liver enzyme inducers is discontinued, the dosage of this product should be redetermined and reduced if necessary. 

3 Phenthiazide, tricyclic antidepressants and some beta-blockers will increase the blood concentration of this product, but do not increase the blood concentration of the antipsychotic active ingredient. 

4 When taken with other highly protein-binding drugs, there is no clinically significant exchange of plasma proteins.