Riluzole NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 10000kg |
Update Time: | 2024-05-18 |
Product Details
Product Name: Riluzole | CAS No.: 1744-22-5 |
EC-No.: 605-724-6 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 10000kg |
Release date: 2024/05/18 |
Factory Provide High Quality API CAS 1744-22-5 Riluzole
Introduction
Product Name :Riluzole
Other name:6-TRIFLUOROMETHOXYBENZOTHIAZOLE-2-YL-AMINE;6-(TRIFLUOROMETHOXY)-1,3-BENZOTHIAZOL-2-AMINE
CAS No.: 1744-22-5
MF:C8H5F3N2OS
MW:234.2
Appearance: White Powder
Melting Point :116-118°C (dec.)(lit.)
Boiling Point :296.3±50.0 °C(Predicted)
Density :1.572±0.06 g/cm3(Predicted)
Storage :Keep in dark place,Sealed in dry,Room Temperature
As a benzothiazole compound, riluzole is the only drug approved by the FDA for the treatment of amyotrophic lateral sclerosis (ALS). It plays a role mainly by regulating glutamate concentration and acting on ion channels. Riluzole has a wide range of pharmacological effects, such as the regulation of glutamate and its transporters, neuroprotective effect, antidepressant, anti anxiety, analgesia and so on.
Function & Application
Riluzole belongs to the derivative of benzothiazole with neuroprotective, potential anti-depressant and anxiolytic activities, which is used in the treatment of a certain type of nerve disease called amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). It is effective to delay the onset of ventilator-dependence or tracheostomy in selected patients, slow down the deterioration of this disease and probably prolong survival by approximately two to three months. Besides, studies have proved that riluzole has anti-depressant activity for refractory depression and serves as an anxiolytic in the treatment of obsessive-compulsive disorder and generalized anxiety disorder.
However, riluzole does not cure the ALS and reverse nerve damage or muscle weakness. It is believed to function as an inhibitor of a natural substance called glutamate. It helps protect the nerves in the brain and spinal cord from too much of glutamate which may contribute to the nerve damage. Riluzole is available in both tablet and liquid form. The liquid formulation may be more suitable for patients with swallowing difficulties.
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