Rhein NEW
| Price | $50 |
| Package | 1mL |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Rhein | CAS No.: 478-43-3 |
| Purity: 98.66% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Rhein |
| Description | Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities. |
| In vitro | In diabetic nephropathy-afflicted db/db mice, Rhein effectively ameliorates diabetic renal lesions and mitigates hyperlipidemia by reducing plasma cholesterol (Chol), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), ApoE, and renal tissue transforming growth factor-β1 (TGF-β1). |
| In vivo | In chondrocytes, Rhein (35 μM) effectively inhibits the synthesis of IL-1β in human osteoarthritis synovium and exerts effects in cartilage by reducing the amount of IL-1R and inhibiting the production of NO induced by IL-1β. Additionally, Rhein is capable of inducing apoptosis in acute promyelocytic leukemia cells (HL-60). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 5.45 mg/mL (19.19 mM), Sonication is recommended. |
| Keywords | Reactive Oxygen Species | Autophagy | Bacterial | Inhibitor | Rhein | NSC-38629 | inhibit | NSC38629 |
| Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Hydroxychloroquine | Guanidine hydrochloride | Doxycycline | Paeonol | Naringin | Dimethyl sulfoxide |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Miao medicine Compound Library | Cosmetic Ingredient Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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