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Postion:Product Catalog >API>Digestive system drugs>Antacid and Mucosal protective Drugs>Rebamipide
Rebamipide
  • Rebamipide

Rebamipide NEW

Price $45
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: Rebamipide CAS No.: 90098-04-7
Purity: 99.9% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱Rebamipide
描述Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度Ethanol : < 1 mg/mL (insoluble or slightly soluble)
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 6.88 mg/mL (18.54 mM), Sonication is recommended.
關(guān)鍵字AGS cells | inhibit | mucosal protection | gastroduodenal ulcer | Inhibitor | COX | Prostaglandin Receptor | OPC-12759 | COX-2 | gastric cancer | Cyclooxygenase | PGE2 | Rebamipide | OPC 12759 | gastritis
相關(guān)產(chǎn)品Ibuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | Paradol | Indomethacin sodium hydrate | Trometamol | Glafenine | Revaprazan hydrochloride
相關(guān)庫經(jīng)典已知活性庫 | 疼痛相關(guān)化合物庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抗癌上市藥物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 | 抗癌藥物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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