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Postion:Product Catalog >Chemical Reagents>Organic reagents>Aromatic acids>(R)-(+)-1,2-Dithiolane-3-pentanoic acid
(R)-(+)-1,2-Dithiolane-3-pentanoic acid
  • (R)-(+)-1,2-Dithiolane-3-pentanoic acid

(R)-(+)-1,2-Dithiolane-3-pentanoic acid NEW

Price $50 $1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2023-12-23

Product Details

Product Name: (R)-(+)-1,2-Dithiolane-3-pentanoic acid CAS No.: 1200-22-2
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2023/12/23
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer

1. Product information

Product Name:(R)-(+)-1,2-Dithiolane-3-pentanoic acid
Synonyms:5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid;5-[(3R)-dithiolan-3-yl]pentanoic acid;5-[(3R)-dithiolan-3-yl]valeric acid;(R)-(+)-1,2-Dithiola;(R)-5-(1,2-Dithiolan-3-yl)pentanoic acid;(R)-Thioctic Acid (R)-1,2-Dithiolane-3-valeric Acid;D-lipoic acid;(R)-(+)-1,2-Dithiolane-3-pentanoic acid 97%
CAS:1200-22-2
MF:C8H14O2S2
MW:206.33
EINECS:638-752-2
Product Categories:API;Sulfur & Selenium Compounds;Chiral Reagents;Chiral Building Blocks;Heterocyclic Building Blocks;Others;FINE Chemical & INTERMEDIATES;Heterocycles;1200-22-2
Mol File:1200-22-2.mol
Article illustration

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Chemical Properties
Melting point 48-52 °C(lit.)
alpha D23 +104° (c = 0.88 in benzene)
Boiling point 185-195 °C(Press: 0.5 Torr)
density 1.218±0.06 g/cm3(Predicted)
refractive index 114 ° (C=1, EtOH)
Fp >230 °F
storage temp. -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO
form Solid
pka5.4(at 25℃)
color Light Yellow to Yellow
optical activity[α]20/D +104°, c = 1 in chloroform
Merck 14,9326
LogP2.160 (est)
CAS DataBase Reference1200-22-2(CAS DataBase Reference)

Safety Information
Risk Statements 22-36/38
Safety Statements 20-36-26-35
WGK Germany 3
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrichEnglish

(R)-(+)-1,2-Dithiolane-3-pentanoic acid Usage And Synthesis
Chemical PropertiesYellow Crystalline Solid
UsesA fat-metabolism stimulator
Usesα-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.
DefinitionChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.
General Descriptionα-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.
Biochem/physiol Actions(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.


2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 

Article illustrationArticle illustration

3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : elin@fdachem.com

Mob: 86 13613820652 

WhatsApp/Skype/Wechat/LINE: 86 13613820652

Article illustration


Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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