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Postion:Product Catalog >API>Antiparasitic drugs>Antimalarial drugs> Pyrimethamine
 Pyrimethamine
  •  Pyrimethamine
  •  Pyrimethamine
  •  Pyrimethamine
  •  Pyrimethamine
  •  Pyrimethamine

Pyrimethamine NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2024-04-11

Product Details

Product Name: Pyrimethamine CAS No.: 58-14-0
EC-No.: 200-364-2 Min. Order: 1kg
Purity: 99% Supply Ability: 1000kg
Release date: 2024/04/11

Manufacturer ProvidPharmaceutical Raw Material CAS 58-14-0 Pyrimethamine with Best Price


Article illustration

Introduction

Product Name:  Pyrimethamine

Other Name :2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;Pyrimethamine

C.A.S NO. :58-14-0

Assay (%)(HPLC, Basis on drying):99%

Appearance:White Powder

MF:C12H13ClN4Article illustration

MW:248.71

Melting Point :233-234°C (dec.)(lit.)

Boiling Point :393.35°C (rough estimate)

Density :1.2171 g/mL at 25 °C(lit.)

Storage Condition: Keep in dark place,Sealed in dry,Room Temperature


Pyrimethamine, also known as immortal, darapirin, is a broad-spectrum veterinary drug widely used for antiprotozoal. In addition, pyrimethamine is also used in aquatic products to enhance the disease resistance of aquatic fish. However, the side effects of pyrimethamine are relatively large. Excessive use can damage the reproductive system of livestock and poultry and is not easy to recover. Pyrimethamine has an inhibitory effect on the primary infrared stage of certain falciparum malaria and vivax malaria, and is a better preventive medicine. Although it has no obvious effect on the gametophytes of malaria parasites, the drug-containing blood enters the mosquitoes, which can affect the development of the gametophytes in the mosquitoes, so it can block transmission.
Pyrimethamine  is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. DHFR is a key enzyme in the redox cycle for production of tetrahydrofolate, a cofactor that is required for the synthesis of DNA and proteins.
This agent is often used in combination with other antimalarials for the treatment of uncomplicated falciparum malaria. Pyrimethamine is used with other medication (such as a sulfonamide) to treat a serious parasite infection (toxoplasmosis) of the body, brain, or eye or to prevent toxoplasmosis infection in people with HIV infection.

Article illustration


Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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