Posaconazole NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 10000kg |
Update Time: | 2024-04-29 |
Product Details
Product Name: Posaconazole | CAS No.: 171228-49-2 |
EC-No.: 682-747-8 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 10000kg |
Release date: 2024/04/29 |
Factory Provide 99% Purity Posaconazole Powder CAS 171228-49-2 Posaconazole
Introduction
Product Name :Posaconazole
CAS No. 171228-49-2
EINECS No. 682-747-8
Molecular Formula: C37H42F2N8O4
MW:700.78
Assay: 99%
Appearance: White powder
Melting Point :170-172 °C
Boiling Point :850.7±75.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
Storage :Keep in a cool, dry, dark location
Posaconazole, launched in the UK, is the newest member of the class of antifungal agents to reach the market. It is indicated for the treatment and prophylaxis of a range of invasive fungal infections, including aspergillosis,fusariosis, chromoblastomycosis, mycetoma, and coccidiomycosis in patients who are refractory to, or intolerant of, standard therapy with amphotericin B and/or itraconazole. In the US, it is approved for the prophylaxis of invasive Aspergillus and Candida infections in patients 13 years of age who are at high risk of developing these infections due to being severely immunocompromised. Additionally, it is approved for the treatment of oropharyngeal candidiasis. Posaconazole has an expanded spectrum of activity over other members of the antifungals. In addition to potent activity against refractory cases of aspergillosis and fluconazole-resistant Candida, it demonstrates activity against Zygomycetes.
Function :
Posaconazole is derived from itraconazole. It is currently undergoing phase III clinical trials. Pharmacological action is the same as azole drugs, but compared with itraconazole, its inhibitory effect on sterol C14 demethylation is stronger, especially for Aspergillus.
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