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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Polymyxin B sulfate
Polymyxin B sulfate
  • Polymyxin B sulfate
  • Polymyxin B sulfate

Polymyxin B sulfate NEW

Price $5 $0.1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-08

Product Details

Product Name: Polymyxin B sulfate CAS No.: 1405-20-5
Min. Order: 1KG Purity: 98%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/08
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details Name: Tina

 1. Materials information

Names

NamePolymyxin B sulfate
SynonymMore Synonyms

 Polymyxin B Sulfate Biological Activity

DescriptionPolymyxin B Sulfate is a cationic surfactant antibiotic agent. A mixture of polymyxins B1 and B2, increases the permeability of the cell membrane.In vitro: RB50 is resistant to killing by polymyxin B at concentrations up to 100 μg/ml.
Related Catalog
Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Others
References

[1]. Rolin O et al. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infect Immun. 2014 Feb;82(2):491-9.

[2]. Pye CC et al. Evaluation of biofilm production by Pseudomonas aeruginosa from canine ears and the impact of biofilm on antimicrobial susceptibility in vitro.Vet Dermatol. 2013 Aug;24(4):446-9

 Chemical & Physical Properties

Boiling Point1651oC at 760 mmHg
Melting Point217-220°C (dec.)
Molecular FormulaC55H96N16O13.H2SO4(PolymyxinB2Sulfate)
Molecular Weight1287.53 (PolymyxinB2Sulfate)
Flash Point952.3oC
PSA573.64000
LogP2.54990
Appearance of Characterspowder
Vapour Pressure0mmHg at 25°C
Storage condition2-8°C
Water SolubilityH2O: 50 mg/mL

 MSDS

Polymyxin B Sulfate MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • TR1150000

  • CHEMICAL NAME :

  • Polymyxin B sulfate

  • CAS REGISTRY NUMBER :

  • 1405-20-5

  • LAST UPDATED :

  • 199504

  • DATA ITEMS CITED :

  • 13

  • MOLECULAR FORMULA :

  • C43-H82-N16-O12.xH2-O4-S

  • MOLECULAR WEIGHT :

  • 1701.97

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 790 mg(base)/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intraperitoneal

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 20500 ug(base)/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Subcutaneous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 59500 ug(base)/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • 5400 ug(base)/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LDLo - Lowest published lethal dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Mammal - dog

  • DOSE/DURATION :

  • 8 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • TYPE OF TEST :

  • LDLo - Lowest published lethal dose

  • ROUTE OF EXPOSURE :

  • Intracerebral

  • SPECIES OBSERVED :

  • Mammal - dog

  • DOSE/DURATION :

  • 320 ug/kg

  • TOXIC EFFECTS :

  • Behavioral - coma

  • TYPE OF TEST :

  • LD50 - Lethal dose, 50 percent kill

  • ROUTE OF EXPOSURE :

  • Subcutaneous

  • SPECIES OBSERVED :

  • Rodent - guinea pig

  • DOSE/DURATION :

  • 58 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

MUTATION DATA

  • TYPE OF TEST :

  • Mutation test systems - not otherwise specified

  • TEST SYSTEM :

  • Yeast - Saccharomyces cerevisiae

  • DOSE/DURATION :

  • 5 mg/L

  • REFERENCE :

  • AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,36,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81938 No. of Facilities: 152 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 967 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9499 No. of Facilities: 383 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1149 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81938 No. of Facilities: 1842 (estimated) No. of Industries: 19 No. of Occupations: 18 No. of Employees: 173376 (estimated) No. of Female Employees: 145041 (estimated)

 Safety Information

SymbolArticle illustration
GHS07
Signal WordWarning
Hazard StatementsH302
Precautionary StatementsP301 + P312 + P330
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn: Harmful;
Risk PhrasesR22
Safety PhrasesS22-S24/25
RIDADR3249
WGK Germany3
RTECSTR1150000
Packaging GroupIII
Hazard Class6.1(b)



2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621








Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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