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Postion:Product Catalog >PI3Kα-IN-9
PI3Kα-IN-9
  • PI3Kα-IN-9

PI3Kα-IN-9 NEW

Price $52 $123 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: PI3Kα-IN-9 CAS No.: 2715287-67-3
Purity: 98.29% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱PI3Kα-IN-9
描述PI3Kα-IN-9 is an orally available, selective and potent PI3Kα inhibitor with antiproliferative activity, inhibits PI3Kα, PI3Kγ, PI3Kδ, and PI3Kβ, induces apoptosis, and can be used in the study of cancer.
體外活性PI3Kα-IN-9 (0-2 μM; 72 hours) inhibited the growth of various cancer cells with IC50 values ranging from 0.43 to 1.33 μM.
體內(nèi)活性In male Sprague-Dawley rats, PI3Kα-IN-9 (1 and 10 mg/kg; oral administration and intravenous injection; for 24 hours) demonstrated favorable pharmacokinetic parameters in vivo[1].
存儲(chǔ)條件Shipping with blue ice.
溶解度DMSO : 80 mg/mL (208.66 mM), Sonication is recommended.
相關(guān)產(chǎn)品Stavudine | 5-Fluorouracil | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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