Product Details
Product Name:
PI-55 |
CAS No.:
1122579-42-3 |
Purity:
98.04% |
Supply Ability:
10g |
Release date:
2024/11/12 |
Product Introduction
Bioactivity
名稱 | PI-55 |
描述 | PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1]. |
體外活性 | High concentrations of PI-55 (10 μM and 100 μM) result in partial inhibition of early haustorial structure development, particularly in the presence of cytokinin. Further, PI-55 treatment, when combined with BAP, diminishes the virulence of P. ramosa compared to the application of BAP alone. This suggests the involvement of histidine kinase receptors analogous to CRE1/AHK4 and AHK3 in the signaling pathway that initiates early haustorial formation [1]. |
存儲條件 | Shipping with blue ice. |
溶解度 | DMSO : 5.83 mg/mL (22.85 mM), Sonication is recommended.
|
關鍵字 | PI-55 | PI55 | PI 55 |
相關庫 | 抗寄生蟲庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 | 抗感染化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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