Pheniramine maleate NEW
| Price | $30 | $56 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: Pheniramine maleate | CAS No.: 132-20-7 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | Pheniramine maleate |
| 描述 | Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived relaxing factor, nitric oxide. |
| 體內(nèi)活性 | Pheniramine maleate binds to histamine H1 receptors, which inhibits the production of phospholipase A2 and the endothelium-derived relaxing factor NO. This leads to a reduction in the activation of guanylate cyclase due to NO deficiency, resulting in decreased levels of cyclic GMP (cGMP). Consequently, this suppresses the contraction of smooth muscle tissues, reduces capillary permeability, and diminishes histamine-induced allergic responses. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 65 mg/mL (182.4 mM) Ethanol : 66 mg/mL (185.2 mM) DMSO : 40 mg/mL (112.23 mM), Sonication is recommended. |
| 關(guān)鍵字 | CNS | Ca2+ influx | antipruritic | first-generation | Histamine Receptor | spinal block | hypnotic | Jurkat ALL | Pheniramine | lumbar puncture | antiemetic | human T-cell acute lymphoblastic leukemia | sedative | BC3H-1 | inhibit | CCRF-CEM | Pheniramine Maleate | Apoptosis | Pheniramine maleate | central nervous system | Inhibitor | Prophenpyridamine | Tripoton |
| 相關(guān)產(chǎn)品 | Alverine citrate | Dapoxetine hydrochloride | Meclizine dihydrochloride | CLOZAPINE N-OXIDE | Lidocaine | Famotidine | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | FDA 上市藥物庫 | 抗癌上市藥物庫 | 已知活性化合物庫 | GPCR靶點分子庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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