P-gp inhibitor 1 NEW
Price | $31 | $76 | $127 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: P-gp inhibitor 1 | CAS No.: 2050747-49-2 |
Purity: 98.65% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | P-gp inhibitor 1 |
Description | P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells). |
In vitro | In K562/A02 MDR cells, P-gp inhibitor 1 (0.1, 1, 5 μM, 1 h) boosts the potency of other MDR-related cytotoxic agents with different structures, increases the accumulation of DOX, blocks Pgp-mediated Rh123 efflux, and suppresses P-gp ATPase activity[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 45 mg/mL (86.94 mM) |
Keywords | P-glycoprotein | inhibit | Pgp inhibitor 1 | Pgp | P-gp | CD243 | MDR1 | Cluster of differentiation 243 | P-gp inhibitor 1 | Multidrug resistance protein 1 | Inhibitor | ABCB1 | P gp inhibitor 1 |
Inhibitors Related | Atazanavir | Selamectin | Verapamil hydrochloride | Glibenclamide | Encequidar mesylate | Verapamil | Polyoxyethylene stearate | Muscone | Elacridar | Piperine | Cinchonine | Atazanavir sulfate |
Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$51.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$8.00/1KG |
VIP2Y
|
Henan Fengda Chemical Co., Ltd
|
2024-04-09 | |
$31.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY