Oxybutynin hydrochloride NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-10-10 |
Product Details
| Product Name: Oxybutynin hydrochloride | CAS No.: 1508-65-2 |
| EC-No.: 216-139-7 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/10/10 |
| CAS: | 1508-65-2 |
| MF: | C22H32ClNO3 |
| MW: | 393.95 |
| EINECS: | 216-139-7 |
| Product Categories: | DITROPAN;Antibiotics;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 1508-65-2.mol |
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| Oxybutynin hydrochloride Chemical Properties |
| Melting point | 122-124°C |
| storage temp. | room temp |
| solubility | H2O: soluble50mg/mL |
| form | powder |
| color | white |
| CAS DataBase Reference | 1508-65-2(CAS DataBase Reference) |
| Oxybutynin hydrochloride Usage And Synthesis |
| Chemical Properties | White to Off-White Solid |
| Originator | Ditropan, Marion , US ,1975 |
| Uses | An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells |
| Uses | anticholinergic |
| Uses | An antagonist of M1, M2, & M3 muscarinic acetylcholine receptors |
| Manufacturing Process | A mixture of 394.2 grams of methyl phenylcyclohexylglycolate and 293.1 grams of 4-diethylamino-2-butynyl acetate was dissolved with warming in 2.6 liters of n-heptane. The solution was heated with stirring to a temperature of 60° to 70°C and 8.0 grams of sodium methoxide were added. The temperature of the mixture was then raised until the solvent began to distill. Distillation was continued at a gradual rate and aliquots of the distillate were successively collected and analyzed for the presence of methyl acetate by measurement of the refractive index. The reaction was completed when methyl acetate no longer distilled, and the refractive index observed was that of pure heptane (nD26 = 1.3855). About 3? hours were required for the reaction to be completed. The reaction mixture was then allowed to cool to room temperature, washed with water, and extracted with four 165 ml portions of 2 N hydrochloric acid. The aqueous extracts were combined and stirred at room temperature to permit crystallization of the hydrochloride salt of the desired product. Crystallization was completed by cooling the slurry in an ice bath, and the product was collected by filtration, pressed dry, and recrystallized from 750 ml of water. Yield of pure crystalline material, 323 grams. |
| Brand name | Ditropan (ALZA). |
| Therapeutic Function | Spasmolytic |
| Biological Activity | oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. |
| Biochem/physiol Actions | Muscarinic acetylcholine receptor antagonist; inhibits proliferation of bladder smooth muscle cells, perhaps by downregulation of growth promoting genes. |
| Clinical Use | Urinary frequency, urgency and incontinence Neurogenic bladder instability and nocturnal enuresis |
| Safety Profile | Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. An eye irritant. Human systemic effects: coma, mydriasis, rate changes. An anticholinergic agent. When heated to decomposition it e |
| Drug interactions | Potentially hazardous interactions with other drugs Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide. Other antimuscarinic agents: increased antimuscarinic effects. |
| Metabolism | Oxybutynin undergoes extensive first-pass metabolism, particularly by the cytochrome P450 isoenzyme CYP3A4. One of the metabolites, N-desethyloxybutynin is pharmacologically active. Oxybutynin and its metabolites are excreted in the urine and faeces. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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