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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Oxolinic acid
Oxolinic acid
  • Oxolinic acid

Oxolinic acid NEW

Price $46
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Oxolinic acid CAS No.: 14698-29-4
Purity: 98.39% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameOxolinic acid
DescriptionOxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
In vitroOxolinic acid, a quinolone antibacterial agent, inhibits reversibly the ATP-dependent replicative DNA synthesis in permeable cell systems as well as in cellophane disk lysates[4]. It also inhibits bacterial DNA gyrase but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 μg/ml[5][6][7].
In vivoThe antimicrobial agent oxolinic acid, injected i.p. in mice, induces a dose dependent increase in locomotor activity. the stimulant locomotor effect of oxolinic acid depends on the blockade of the neuronal dopamine uptake complex[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : < 1 mg/mL (insoluble)
KeywordsDNA/RNA Synthesis | dopamine | inhibit | DNA/RNA | Bacterial | NSC-110364 | Inhibitor | uptake | antimicrobial | Antibiotic | NSC110364 | urinary | Oxolinic acid | infections | tract | synthesis
Inhibitors RelatedNeomycin sulfate | Kanamycin sulfate | Sulfamethoxazole sodium | Guanidine hydrochloride | Doxycycline | Thymidine | Dimethyl sulfoxide
Related Compound LibrariesPesticide Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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