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Postion:Product Catalog >ONO-7300243
ONO-7300243
  • ONO-7300243

ONO-7300243 NEW

Price $38 $88 $135
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ONO-7300243 CAS No.: 638132-34-0
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameONO-7300243
DescriptionONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).
In vivoThe oral administration of ONO-7300243 (17a) to determine its effect on rat IUP. Compound 17a inhibited the LPA-induced IUP increase in a dose-dependent manner (ID50 = 11.6 mg/kg p.o.) up to 1 h after dosing. Significant effects were observed at 10 and 30 mg/kg (p < 0.05 vs vehicle). ONO-7300243 (17a) (30 mg/kg, p.o.) led to a significant decrease in the IUP in conscious rats without LPA stimulation compared with the vehicle without affecting the mean blood pressure (MBP)[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (216.66 mM)
KeywordsONO-7300243 | inhibit | Inhibitor | ONO 7300243 | LPL Receptor | ONO7300243 | Lysophospholipid Receptor
Inhibitors RelatedRadioprotectin-1 | Fingolimod hydrochloride | SLP9101555 | Tyloxapol | ASP-4058 | Ki16198 | CYM50260 | Tetradecyl Phosphonate | Siponimod | Fingolimod | S1PR1 modulator 1 | Ozanimod
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Fibrosis Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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