Obtusifolin NEW
Price | $64 | $197 | $293 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: Obtusifolin | CAS No.: 477-85-0 |
Purity: 99.79% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
Name | Obtusifolin |
Description | 1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be a novel anti-breast-cancer bone metastasis agent. 3. Obtusifolin has beneficial effects on the development of diabetic retinopathy via inhibition of accumulation of oxidatively modified DNA and nitrotyrosine in the retina, can help prevent vision loss in diabetic patients. 4. Obtusifolin and gluco-Obtusifolin produce significant antinociceptive action in rodent behavioral models of inflammatory/neuropathic pain, and that this activity is associated with modulation of neuroinflammation in spinal cord. 5. Gluco-Obtusifolin and its aglycone may be useful for the treatment of cognitive impairment, and that its beneficial effects are mediated, in part, by the enhancement of cholinergic signaling. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 23 mg/mL (80.9 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble |
Keywords | Nuclear factor-κB | epithelial | Nuclear factor-kappaB | NF-κB | Inhibitor | inhibit | breast | cancer | mucin | Obtusifolin | esters | airway | bone | phthalate | metastasis | MUC5AC |
Inhibitors Related | Thiamine monochloride | Butylated hydroxytoluene | Diethylmaleate | Propyl gallate | L-Tartaric acid | Glucosamine | Neohesperidin | Sulbutiamine | Lidocaine hydrochloride | L-Cystine | Indole-3-carbinol | Diallyl disulfide |
Related Compound Libraries | 抗癌天然產(chǎn)物庫 | 經(jīng)典已知活性庫 | 中藥單體化合物庫 | 天然產(chǎn)物庫 | 抑制劑庫 | 高通量篩選天然產(chǎn)物庫 | 抗衰老化合物庫 | 古代經(jīng)典名方目錄分子庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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