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Postion:Product Catalog >OATD-01
OATD-01
  • OATD-01

OATD-01 NEW

Price $51 $74 $122
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: OATD-01 CAS No.: 2088453-21-6
Purity: 99.59% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱OATD-01
描述OATD-01 is a highly active inhibitor of both Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase).
體外活性The Ki values for hCHIT1,mCHIT1, hAMCase and mAMCase are 17.3 nM, 26.05 nM, 4.8 nM and 5.7 nM, respectively[1]. These Ki values reveals good correlation with earlier established IC50 data, which are 23 nM, 28 nM, 9 nM and 7.8 nM, respectively[1]. OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets[1].
體內(nèi)活性OATD-01 given orally once daily in a range of doses between 30 and 100 mg/kg showed significant antifibrotic efficacy in an animal model of bleomycin-induced pulmonary fibrosis[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 85 mg/ml (217.44 mM)
關(guān)鍵字inhibit | OATD 01 | CHIT1 | chitinase | antifibrotic | OATD-01 | IPF | pulmonary fibrosis | OATD01 | Inhibitor
相關(guān)庫經(jīng)典已知活性庫 | 抑制劑庫 | 口服活性化合物庫 | 已知活性化合物庫 | 臨床前化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$0.00/50mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$259.00/5mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
$0.00/1kg
Nanjing Fred Technology Co., Ltd
2024-01-02
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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