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Postion:Product Catalog >NS3694
NS3694
  • NS3694

NS3694 NEW

Price $31 $44 $72
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-12

Product Details

Product Name: NS3694 CAS No.: 426834-38-0
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/12

Product Introduction

Bioactivity

名稱NS3694
描述NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.
體外活性NS3694 (10, 50, and 100 μM) specifically inhibits cytochrome c- and dATP-induced DEVDase activation and processing of caspases and caspase substrates, thus inhibiting the mitochondria-mediated apoptosis. NS3694 inhibits the formation of the apoptosome Apaf-1 by blocking the activation of the initiator caspase-9. In MCF-casp3 cells, NS3694 (10-100 μM) inhibits dose-dependently caspase 9, 3, and 7 processing, DFF45/ICAD, and PARP cleavage, and DEVDase activity and inhibits TNF-induced effector caspase activation and apoptosis[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (153.33 mM)
關(guān)鍵字Inhibitor | NS-3694 | Apaf-1 | Apoptosis | inhibit | caspase-9 | NS 3694 | apoptosome inhibitor | NS3694 | cytochrome c
相關(guān)產(chǎn)品Stavudine | 5-Fluorouracil | Acetylcysteine | Kaempferol | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Lidocaine hydrochloride
相關(guān)庫經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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