Product Details
Product Name:
NS-3-008 hydrochloride |
CAS No.:
1172854-54-4 |
Purity:
99.56% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | NS-3-008 hydrochloride |
Description | NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM). |
In vivo | Administration of NS-3-008 inhibited the expression of G0s2 in healthy mice liver.?In contrast, administration of NS-3-008 did not affect the MBP in wild-type sham and 5/6Nx mice.?NS-3-008 as a novel G0s2 inhibitor and showed that administration of this inhibitor ameliorated renal dysfunction in wild-type 5/6Nx mice. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 120 mg/mL (444.76 mM), Sonication is recommended. H2O : 125 mg/mL (463.29 mM), Sonication is recommended.
|
Keywords | renal | inhibit | Ccl2 | NS3008 hydrochloride | Hsd17b4 | Stat5 | transcriptional | Inhibitor | NS-3-008 Hydrochloride | dysfunction | ameliorate | CKD | NS 3 008 hydrochloride | p65 | G0s2 |
Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:123653-11-2
$46.00 / 5mg
-
CAS:153587-01-0
$31.00 / 1mg
-
CAS:2249106-01-0
$56.00 / 1mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$0.00/1g |
VIP1Y
|
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
|
2024-11-15 |
|
$50.00/1kg |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-03-22 |
|
$20.00/1kg |
VIP5Y
|
Hebei Yanxi Chemical Co., Ltd.
|
2023-11-28 |