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Postion:Product Catalog >API>Circulatory system drugs>Anti Shock vasoactive drugs>Norepinephrine
Norepinephrine
  • Norepinephrine
  • Norepinephrine
  • Norepinephrine
  • Norepinephrine
  • Norepinephrine

Norepinephrine NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-08-30

Product Details

Product Name: Norepinephrine CAS No.: 51-41-2
EC-No.: 200-096-6 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/08/30

CAS:51-41-2
MF:C8H11NO3
MW:169.18
EINECS:200-096-6
Product Categories:chiral
Mol File:51-41-2.mol
Article illustration

Norepinephrine Chemical Properties
Melting point 220-230°C
alpha D25 -37.3° (c = 5 in water with 1 equiv HCl)
Boiling point 298.46°C (rough estimate)
density 1.2435 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. 2-8°C
solubility Aqueous Acid (Slightly), DMSO (Slightly)
form crystalline
pka8.64(at 25℃)
color off-white to tan
Water Solubility Soluble in alkali and dilute hydrochloric acid. Slightly soluble in water, ethanol and diethyl ether.
Sensitive Air & Light Sensitive
Merck 14,6695
BRN 4231961
Stability:Stable, but may be light-sensitive. Incompatible with acids, bases, oxidizing agents. Store at -20℃.
CAS DataBase Reference51-41-2(CAS DataBase Reference)
EPA Substance Registry SystemNorepinephrine (51-41-2)

Norepinephrine Usage And Synthesis
Chemical Propertiessolid
UsesVascular active drug resistance to shock
UsesAn adrenergic neurotransmitter.
UsesNorepinephrine is used for increasing cardiac constriction and for the necessary elevation of blood pressure after sharp decline, which can result from surgical intervention or trauma.
DefinitionChEBI: The R-enantiomer of noradrenaline.
Brand nameLevophed (Hospira);Noradrec;Xylotox.
World Health Organization (WHO)Vasoconstrictor agents have been in use for many years to prolong duration of action of local anaesthetics, particularly in dentistry. Combination products containing epinephrine or levarterenol in concentrations of 1:80,000 or less remain widely available. See also WHO comment for epinephrine.
Biological FunctionsMost central noradrenergic neurons are located in the nucleus locus ceruleus of the pons and in neurons of the reticular formation. Fibers from these nuclei innervate a large number of cortical, subcortical, and spinomedullary fields. Many functions have been ascribed to the central noradrenergic neurons, including a role in affective disorders (see Chapter 33), in learning and memory, and in sleep–wake cycle regulation.The mammalian CNS contains both α- and β-adrenoceptors.
General DescriptionNorepinephrine (NE, Levophed) differs from DA onlyby addition of a 1-OH substituent (β-OH-DA) and from Eonly by lacking the N-methyl group. Like DA, it is polar andrapidly metabolized by both COMT and MAO, resulting inpoor oral bioavailability and short DOA (1 or 2 minutes evenwhen given intravenously). It is a stimulant of α1-, α2-, andβ1-adrenoceptors (notice that lacking the N-methyl group resultsin lacking β2- and β3-activity). It is used to counteractvarious hypotensive crises, because its α-activity raisesblood pressure and as an adjunct treatment in cardiac arrestbecause its β-activity stimulates the heart. It has limitedclinical application caused by the nonselective nature of itsactivities.
HazardMay cause local tissue necrosis, headache, bradycardia, hypertension; poison; teratogen; mutagen.
Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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