Nerol NEW
| Price | $36 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-06 |
Product Details
| Product Name: Nerol | CAS No.: 106-25-2 |
| Purity: 98.59% | Supply Ability: 10g |
| Release date: 2024/11/06 |
Product Introduction
Bioactivity
| 名稱 | Nerol |
| 描述 | Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart. |
| 動物實驗 | Guinea pigs were sacrificed by decapitation and hearts were removed and isolated left atrium mounted vertically in an organ baths containing Tyrode's solution of the following composition (mM): NaCl 120, KCl 2.7, MgCl2 0.9, NaHCO3 11.9, CaCl2 1.37, glucose 5.5, NaH2PO4 0.4, pH 7.4. The atria preparations were subsequently connected to Grass FI'-03 force displacement transducers to record changes in atrial contractile force. Each muscle was stretched to the length at which contractile force was maximal (1.0 gf). The atria were electrically paced at 1 Hz with pulses of 1.5 ms duration and stimulated by 70 V pulses. All preparations were allowed to equilibrate for 30 min until complete mechanical stabilization had been achieved. Nerol ( 97%) was freshly solubilized in 0.5% DMSO and cumulatively added to bath chambers. After each observation, muscles were washed several times and allowed to recover for 30 minutes until their mechanical function completely returned to control values. DMSO at this concentration did not show any significant effect on the variables measured (data not shown, n = 5). |
| 體內活性 | Nerol primarily by reducing Ca2+ influx through L-type Ca2+ channel blockade lessened the severity of ouabain-triggered arrhythmias in mammalian heart. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 45 mg/mL (291.73 mM) |
| 關鍵字 | Antifungal | inhibit | Fungal | Reactive Oxygen Species | Inhibitor | mitochondrial | Nerol | Calcium | dysfunction | Apoptosis | NEL | Endogenous Metabolite | ROS | Mitochondrial Metabolism |
| 相關產品 | Sucrose | Stavudine | Daidzein | Guanidine hydrochloride | Fumaric acid | Tributyrin | Ferulic Acid | Glycerol | Thymidine | Naringin |
| 相關庫 | 中藥單體化合物庫 | 植物來源化合物庫 | 抗真菌庫 | 苗藥化合物庫 | 中藥抗炎分子庫 | 煙草單體化合物庫 | 高通量篩選天然產物庫 | 抗感染天然產物庫 | 已知活性化合物庫 | 古代經典名方目錄分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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