Natamycin NEW
| Price | $38 | $54 | $80 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: Natamycin | CAS No.: 7681-93-8 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | Natamycin |
| 描述 | Natamycin (Pimaricin) is a Polyene Antimicrobial. |
| 體內(nèi)活性 | Under conditions where growth is inhibited, Natamycin does not affect the permeability of yeast cell membranes. Natamycin impedes the initiation phase of vacuole fusion, preventing the joining of separate vacuoles without damaging the barrier function of the vacuolar membrane. It disrupts vacuole morphology within the yeast cells, resulting in the formation of numerous smaller vacuole structures. Natamycin specifically binds to ergosterol on model membranes. It exhibits a lower minimum inhibitory concentration (MIC) for dematiaceous fungi and species of Curvularia. The solubility and stability of Natamycin in aqueous solutions are enhanced through the formation of a complex with γ-cyclodextrin, which also reduces drug side effects without compromising antifungal activity. The MIC90 of both Natamycin and its complex with Natamycin-γ cyclodextrin (Natamycin-γ CyD) is below 0.0313 mg/ml, indicating that γ CyD significantly enhances the antifungal activity of Natamycin, thus affirming the clinical utility of the Natamycin-gamma CyD complex. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 1 mg/ml, Sonication is recommended. |
| 關(guān)鍵字 | Antibiotic | inhibit | Fungal | Endogenous Metabolite | Inhibitor | Natamycin |
| 相關(guān)庫 | 抗癌天然產(chǎn)物庫 | 農(nóng)藥化合物庫 | 經(jīng)典已知活性庫 | 抗真菌庫 | 天然產(chǎn)物庫 | 藥物功能重定位化合物庫 | 高通量篩選天然產(chǎn)物庫 | FDA 上市藥物庫 | 抗感染天然產(chǎn)物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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