NAPHTHOQUINE PHOSPHATE NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-08-31 |
Product Details
| Product Name: NAPHTHOQUINE PHOSPHATE | CAS No.: 173531-58-3 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: 50000KG/month | Release date: 2023/08/31 |
| CAS: | 173531-58-3 |
| MF: | C24H31ClN3O5P |
| MW: | 507.95 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 173531-58-3.mol |
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| NAPHTHOQUINE PHOSPHATE Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble in DMSO |
| form | Powder |
| NAPHTHOQUINE PHOSPHATE Usage And Synthesis |
| Biological Activity | malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. naphthoquine phosphate is a antimalarial drug developed in china. |
| in vitro | naphthoquine phosphate showed promising antimalaria acitivities against various p. falciparum strains. moreover, previoius study highlighted that naphthoquine did not lose potency when tested against chloroquine resistant strains [1]. |
| in vivo | in an study aiming to investigate the antimalarial activity of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi in rhesus monkey, it was found that the combination of naphthoquine phosphate and artemisinine was superior to the single component and the optimum proportion in the combination is 1 : 2.5 in treating p. knowlesi infection in monkeys [2]. |
| target | malaria |
| IC 50 | 0.1-5.2 nm for various p. falciparum strains [1] |
| references | [1] delves m, plouffe d, scheurer c, meister s, wittlin s, winzeler ea, sinden re, leroy d. the activities of current antimalarial drugs on the life cycle stages of plasmodium: a comparative study with human and rodent parasites. plos med. 2012;9(2):e1001169. [2] wang jy, ding db, li gf, zhao jh. therapeutic efficacy of naphthoquine phosphate combined with artemisinine against plasmodium knowlesi. zhongguo ji sheng chong xue yu ji sheng chong bing za zhi. 2008;26(6):442-4. [3] tun t, tint hs, lin k, kyaw tt, myint mk, khaing w, tun zw. efficacy of oral single dose therapy with artemisinin-naphthoquine phosphate in uncomplicated falciparum malaria. acta trop. 2009;111(3):275-8. |
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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