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Postion:Product Catalog >N-Desmethyl Sildenafil
N-Desmethyl Sildenafil
  • N-Desmethyl Sildenafil

N-Desmethyl Sildenafil NEW

Price $35 $58 $93
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: N-Desmethyl Sildenafil CAS No.: 139755-82-1
Purity: 99.68% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameN-Desmethyl Sildenafil
DescriptionN-Desmethyl Sildenafil is the major metabolite of Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor.
In vitroN-Desmethyl Sildenafil enhances the amplitude of electroretinogram (ERG) signals from dark-adapted isolated rat retinas, likely by improving photoreceptor cell responses[1]. This compound's formation is investigated through the use of CYP3A supersomes that co-express human P450 oxidoreductase and cytochrome b5, with its synthesis being predominantly catalyzed by CYP3A4 and CYP3A5 enzymes, and to a smaller degree by CYP3A7[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMF : 5 mg/mL
DMSO:PBS (pH 7.2)(1:5) : 0.15 mg/mL
DMSO : 225 mg/mL (488.5 mM), Sonication is recommended.
KeywordsN-Desmethyl Sildenafil
Inhibitors RelatedNortriptyline hydrochloride | Clofibric acid | Oseltamivir acid | Mycophenolate Mofetil | CLOZAPINE N-OXIDE | Monomethyl fumarate | Isonicotinic acid | Ampyrone | 4-Methylamino antipyrine | Nicotinamide N-oxide
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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