Product Details
Product Name:
Minnelide |
CAS No.:
1254702-87-8 |
Purity:
99.59% |
Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
名稱(chēng) | Minnelide |
描述 | Minnelide is a water-soluble tretinoin lactone prodrug with anticancer and antitumor activity that induces apoptosis and may prevent podocyte damage.Minnelide inhibits cervical cancer growth by blocking HPV-induced changes in p53 and pRb. |
體外活性 | Minnelide (0.100 nM, 200 nM; 48 hours) decreased cell viability in vitro in the pancreatic cancer cell lines S2-013, MIA PaCa-2, S2-VP10, and Panc-1[2]. |
體內(nèi)活性 | In the orthotopic model of pancreatic cancer with MIA PaCa-2-derived human pancreatic tumors in athymic nude mice, Minnelide (0.1-0.6 mg/kg; intraperitoneal injection; once daily or twice daily) was able to inhibit pancreatic tumor growth in vivo[2]. |
存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 10 mg/mL (19.44 mM), Sonication is recommended. H2O : 80 mg/mL (155.53 mM), Sonication is recommended.
|
關(guān)鍵字 | Minnelide |
相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Phenytoin sodium | Myricetin | Meclizine dihydrochloride | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
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Suppliers |
Update time |
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$/ |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |