成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >API>Hormones and the Endocrine System>Estrogen and progestin drugs>Medroxyprogesterone Acetate
Medroxyprogesterone Acetate
  • Medroxyprogesterone Acetate

Medroxyprogesterone Acetate NEW

Price $29
Package 1mL
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Medroxyprogesterone Acetate CAS No.: 71-58-9
Purity: 99.45% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMedroxyprogesterone Acetate
DescriptionMedroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.
In vitroMedroxyprogesterone acetate (MPA) and progesterone significantly reduced the levels of glutamic acid decarboxylase (GAD) in the hippocampus, while markedly increasing GAD levels in the olfactory cortex. In aged ovariectomized rats, MPA impaired the retention of delayed memory in the swim arm task and exacerbated overnight forgetting in the Morris water maze.
In vivoMedroxyprogesterone acetate (MPA) reduces the secretion of IL-6 and PTHrP in human breast cancer cells and downregulates their expression in KTC-2 cells in a dose-dependent manner. In M-1 cells, MPA and dexamethasone increase the promoter-driven luciferase activity of α-ENaC in a dose-dependent fashion, an effect which is not inhibited by Org31710, indicating that MPA's regulation of α-ENaC is independent of the progesterone receptor (PR). Similarly, MPA and dexamethasone upregulate the mRNA of α-ENaC and SGK1 in both M-1 and Madin-Darby canine kidney-C7 cells, whereas progesterone does not exhibit this effect. At 0.1 nM, MPA significantly enhances the in vitro production of specific immunoglobulin G antibodies, an effect that seems to involve the interaction between progesterone and the PRG receptor. MPA also inhibits the enzyme 3-hydroxysteroid dehydrogenase, which is involved in the reversible conversion between THP and DHP, thereby potentially affecting the action of DHP and THP in the brain.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 9 mg/mL (23.28 mM), Sonication is recommended.
Ethanol : 10 mg/mL (25.9 mM)
KeywordsMedroxyprogesterone Acetate | Inhibitor | Androgen Receptor | Endogenous Metabolite | Glucocorticoid Receptor | NSC26386 | Medroxyprogesterone | Progesterone Receptor | NR3C3 | inhibit | NSC 26386
Inhibitors RelatedSucrose | Ferulic Acid | Glycerol | Thymidine
Related Compound LibrariesAnti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Natural Product Library for HTS | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$29.00/1mL
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$100.00/1kg
VIP1Y
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2024-08-21
$0.00/1Kg/Bag
VIP4Y
Sinoway Industrial co., ltd.
2024-06-27
$0.00/1kg
VIP1Y
Shaanxi TNJONE Pharmaceutical Co., Ltd
2024-05-21
$10.00/1kg
Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-29
$0.00/1G
VIP1Y
CONTIDE BIOTECH CO.,LTD
2024-04-12
$200.00/1kg
VIP1Y
Hebei Kangcang new material Technology Co., LTD
2024-03-22
$45.00/1kg
VIP1Y
Sigma Audley
2024-03-07
$10.00/1kg
Nantong Guangyuan Chemicl Co,Ltd
2023-11-03
$85.00/1kg
VIP2Y
Zibo Hangyu Biotechnology Development Co., Ltd
2023-10-27
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY