m-PEG12-DBCO NEW
Price | $59 | $86 | $142 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-07 |
Product Details
Product Name: m-PEG12-DBCO | Supply Ability: 10g |
Release date: 2024/11/07 |
Product Introduction
Bioactivity
名稱 | m-PEG12-DBCO |
描述 | m-PEG12-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
體外活性 | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins[1]. |
存儲條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 200 mg/mL (236.13 mM), Sonication is recommended. |
關(guān)鍵字 | m PEG12 DBCO | m-PEG12-DBCO | m-PEG-12-DBCO | mPEG12DBCO |
相關(guān)產(chǎn)品 | ARV-393 HCl | Gefitinib-based PROTAC 3 | ACBI1 | ARV-471 | dBET6 | dBET1 | ARV-825 | β-NF-JQ1 | C004019 | GMB-475 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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