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Postion:Product Catalog >LPA1 receptor antagonist 1
LPA1 receptor antagonist 1
  • LPA1 receptor antagonist 1

LPA1 receptor antagonist 1 NEW

Price $147 $367 $587
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: LPA1 receptor antagonist 1 CAS No.: 1396006-71-5
Purity: 99.58% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameLPA1 receptor antagonist 1
DescriptionLPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis.
In vitroCompared to Ki16425 and AM095, LPA1 receptor antagonist 1 demonstrates superior anti-proliferative activity. It exhibits the highest selectivity for LPA1 and efficiently inhibits LPA-induced NHLF proliferation and contraction[1]. Similarly, LPA1 receptor antagonist 1 (compound 2) shows highly specific inhibitory activity against LPA1, with minimal inhibition of LPA3 even at relatively high concentrations.[1].
In vivoOral administration of LPA1 receptor antagonist 1 (compound 2) to mice led to a dose-dependent reduction in plasma histamine levels in a murine LPA challenge model [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsLPA1 receptor antagonist 1 | LPA-1 receptor antagonist 1 | LPA1 antagonist 1
Inhibitors RelatedRadioprotectin-1 | DBIBB | AM966 | Ki16198 | Tetradecyl Phosphonate | LPA2 antagonist 2 | GRI977143 | UCM-05194 | H2L5186303 | Ki16425
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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