LPA1 receptor antagonist 1 NEW
Price | $147 | $367 | $587 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-20 |
Product Details
Product Name: LPA1 receptor antagonist 1 | CAS No.: 1396006-71-5 |
Purity: 99.58% | Supply Ability: 10g |
Release date: 2024/11/20 |
Product Introduction
Bioactivity
Name | LPA1 receptor antagonist 1 |
Description | LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. |
In vitro | Compared to Ki16425 and AM095, LPA1 receptor antagonist 1 demonstrates superior anti-proliferative activity. It exhibits the highest selectivity for LPA1 and efficiently inhibits LPA-induced NHLF proliferation and contraction[1]. Similarly, LPA1 receptor antagonist 1 (compound 2) shows highly specific inhibitory activity against LPA1, with minimal inhibition of LPA3 even at relatively high concentrations.[1]. |
In vivo | Oral administration of LPA1 receptor antagonist 1 (compound 2) to mice led to a dose-dependent reduction in plasma histamine levels in a murine LPA challenge model [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | LPA1 receptor antagonist 1 | LPA-1 receptor antagonist 1 | LPA1 antagonist 1 |
Inhibitors Related | Radioprotectin-1 | DBIBB | AM966 | Ki16198 | Tetradecyl Phosphonate | LPA2 antagonist 2 | GRI977143 | UCM-05194 | H2L5186303 | Ki16425 |
Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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