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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>5-HT Receptor Antagonists>Loxapine succinate
Loxapine succinate
  • Loxapine succinate

Loxapine succinate NEW

Price $33 $47 $76
Package 50mg 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Loxapine succinate CAS No.: 27833-64-3
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLoxapine succinate
DescriptionLoxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
In vitroIn rats, subcutaneous injection of Loxapine (0.3 mg/kg) induces general stiffness. In the rat brain, administering Loxapine (5 mg/kg) does not alter dopamine receptor density, but it reduces serotonin receptor density.
In vivoLoxapine effectively facilitates the binding of [3H]ketanserin to 5-HT2 receptors in both the human frontal cortex (ki=6.2 nM) and the bovine frontal cortex (ki=6.6 nM). Additionally, in LPS-activated mixed glial cells, loxapine at concentrations of 0.2 μM, 2 μM, and 20 μM, successfully reduces the secretion of IL-1β and IL-2.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 2 mg/mL (4.48 mM)
DMSO : 82 mg/mL (183.9 mM)
Keywords5-HT Receptor | antipsychotics | 5-hydroxytryptamine Receptor | Loxapine | serotonin | Loxapine succinate | Serotonin Receptor | Inhibitor | inhibit | Dopamine Receptor | schizophrenia | IL-2 | Loxapine Succinate | IL-1β
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | Octopamine hydrochloride | Oxolinic acid
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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