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Postion:Product Catalog >API>Circulatory system drugs>Lipid regulating drugs>Linoleic acid
Linoleic acid
  • Linoleic acid

Linoleic acid NEW

Price $48
Package 1g
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: Linoleic acid CAS No.: 60-33-3
Purity: 99.61% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱Linoleic acid
描述Linoleic acid (9,12-octadecadienoic acid) is a naturally occurring polyunsaturated fatty acid found in animal and vegetable oils. Linoleic acid is an essential fatty acid that is part of membrane phospholipids.
體外活性METHODS: Bovine satellite cell BSCs were treated with Linoleic acid (10-250 μM) for 24-48 h. Cell viability was measured by MTT assay. RESULTS: At 24 h of treatment with Linoleic acid, cell proliferation increased at doses of 10-100 μM and decreased at 250 μM as compared to untreated control. 100 μM Linoleic acid at 48 h had no significant effect on cell proliferation. [1] METHODS: Human ovarian cancer cells SKOV-3 were treated with Linoleic acid (16 μM) for 24 h. Cell migration was detected by wound-healing assay. RESULTS: The average migration in the Linoleic acid treated group increased by about 20% on average compared to control untreated cells. [2]
體內(nèi)活性METHODS: To study the effects on endocannabinoid (EC) biology, four groups of C57BL/6 mice were fed diets containing 1% or 8% Linoleic acid (with or without G (LAG)) for eight weeks. RESULTS: Increasing dietary Linoleic acid from 1% to 8% significantly increased circulatory, small intestinal, and hepatic ECS. 1% LAG-fed mice had the lowest feed efficiencies, and hepatic levels of only two ECs were reduced by the addition of G. [3]
存儲條件keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (196.11 mM)
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4.33 mg/mL (15.44 mM), Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately.
關(guān)鍵字polyunsaturated | omega-6 | acid | metabolite | arachidonic acid | inhibit | Inhibitor | fatty | Endogenous Metabolite | oils | endogenous | essential | Linoleic acid | nutrient | human | plant
相關(guān)庫經(jīng)典已知活性庫 | 中藥單體化合物庫 | 風(fēng)味化合物庫 | 食品添加劑化合物庫 | 煙草單體化合物庫 | 高通量篩選天然產(chǎn)物庫 | 化妝品成分化合物庫 | 已知活性化合物庫 | 古代經(jīng)典名方目錄分子庫 | 藥食同源庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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