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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>Linagliptin
Linagliptin
  • Linagliptin
  • Linagliptin
  • Linagliptin
  • Linagliptin
  • Linagliptin

Linagliptin NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 10000kg
Update Time: 2024-04-13

Product Details

Product Name: Linagliptin CAS No.: 668270-12-0
EC-No.: 1308068-626-2 Min. Order: 1kg
Purity: 99% Supply Ability: 10000kg
Release date: 2024/04/13

Manufacturer Provide Raw Material Linagliptin Powder CAS 668270-12-0 Linagliptin


Article illustration

Introduction

Product Name: Linagliptin

Other Name :Linagliptin; (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

CAS NO:668270-12-0

Purity: 99%min
Appearance:White crystalline powder

Molecular formula: C25H28N8O2

Article illustration

MW:472.54

Melting Point :202 oC

Boiling Point :661.2±65.0 °C(Predicted)

Density:1.39

Storage :Keep in dark place,Inert atmosphere,Room temperature

Linagliptin (trade names Tradjenta and Trajetna) is an inhibitor of dipeptidyl peptidase-4 (DPP-4) that was approved by the U.S. FDA in May 2011 for the treatment of Type 2 diabetes along with diet and exercise. Linagliptin (BI-1356) has been described as a potent highly selective, slow-off rate and long acting inhibitor of DPP-4.

Application

Linagliptin arose from optimization efforts of xanthine-based DPP-4 inhibitors with the initial lead identified from an HTS campaign. After optimizing the activity of the initial micromolar lead, two issues that needed to be addressed were activity for hERG and muscarinic receptor M1.Article illustration



Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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