L-Cysteinesulfinic acid monohydrate NEW
| Price | $31 | $56 | $93 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: L-Cysteinesulfinic acid monohydrate | CAS No.: 207121-48-0 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | L-Cysteinesulfinic acid monohydrate |
| 描述 | L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively [1]. |
| 體外活性 | L-Cysteinesulfinic acid (monohydrate) serves as an innate activator for the phospholipase D (PLD)-linked metabotropic excitatory amino acids (EAA) receptor, selectively triggering the PLD-associated mechanism. When applied to hippocampal slices, 1 mM concentrations of L-CSA (monohydrate) significantly enhance PLD activity, unlike similar doses of L-glutamate, L-aspartate, and L-HCA, which show no effect. Furthermore, L-CSA (monohydrate) prompts a dose-responsive elevation in PLD activity in these slices, even when iGluR antagonists are present, with the potency around an EC50 of 500 uM. Notably, the response to 1 mM L-CSA (monohydrate) in augmenting PLD activity remains unaltered by 1 uM tetrodotoxin, indicating that the effect is not reliant on an increase in neuronal activity[1]. |
| 存儲條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 120 mg/mL (701.06 mM), Sonication is recommended. |
| 關鍵字 | L Cysteinesulfinic acid monohydrate | LCysteinesulfinic acid monohydrate | Metabotropic glutamate receptors | Inhibitor | inhibit | L-Cysteinesulfinic acid Monohydrate | L-Cysteinesulfinic acid | mGluR |
| 相關產品 | IDRA-21 | Decanoic Acid | L-Cysteic acid monohydrate | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine | Memantine hydrochloride |
| 相關庫 | 經典已知活性庫 | 神經退行性疾病化合物庫 | 神經信號分子庫 | 膜蛋白靶向化合物庫 | 神經遞質受體化合物庫 | 已知活性化合物庫 | 小鼠代謝化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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