Kisspeptin-10, human (TFA)(374675-21-5,FREE) NEW
Price | $115 | $385 | $577 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: Kisspeptin-10, human (TFA)(374675-21-5,FREE) | Purity: 100% |
Supply Ability: 10g | Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | Kisspeptin-10, human (TFA)(374675-21-5,FREE) |
描述 | Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression |
體外活性 | KP-10-treatment significantly increased the expression of osteogenic genes, including mRNA and protein levels of BMP2, in C3H10T1/2 cells.?Moreover, KP-10 induced BMP2-luc activity and increased phosphorylation of Smad1/5/9.?In addition, NFATc4 specifically mediated KP-10-induced BMP2 gene expression.?However, KP-10 treatment did not induce expression of the BMP2 and Runx2 genes in GPR54-/- cells.?To examine whether KP-10 induced secretion of BMP2 to the culture medium, we used the conditioned-medium (C.M) of KP-10 treated medium on C3H10T1/2 cells.?Dlx5 and Runx2 expressions were higher in GPR54-/- cells treated with C.M than in those treated with KP-10[1]. |
存儲條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 4 mg/mL (2.82 mM), Sonication is recommended. |
關鍵字 | Kisspeptin 10, human (TFA)(374675 21 5,FREE) | Kisspeptin10, human (TFA)(374675215,FREE) | Kisspeptin-10, human (TFA)(374675-21-5,FREE) |
相關產(chǎn)品 | Vincamine | Monomethyl fumarate | Questiomycin A | Benzyl nicotinate | TUG-1375 |
相關庫 | 經(jīng)典已知活性庫 | 多肽分子庫 | 內分泌激素分子庫 | NO PAINS 化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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