Product Details
Product Name:
KGP94 |
CAS No.:
1131456-28-4 |
Purity:
98.52% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | KGP94 |
Description | KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme. |
In vitro | The novel cathepsin L/K inhibitors KGP94 could inhibit in vitro M2 macrophage invasion and reduce the macrophage-stimulated invasion of 4T1 murine breast cancer cells. KGP94 treatment also reduced the expression of several M2-associated markers, suggesting that cathepsin L activity may be important for IL-4-driven M0 to M2 differentiation[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/ml (171.32 mM)
|
Keywords | Inhibitor | M2 marker | Metastasis | Raw264.7 macrophage | metastatic carcinoma | Cathepsin | inhibit | prostate (PC-3ML) | Cathepsin L | KGP94 | breast cancer cell |
Inhibitors Related | Papain | 2-Aminoethanethiol | (S)-(+)-Ibuprofen | PMSF | N-Ethylmaleimide | Z-Lys-OH | FMK 9a | Leupeptin Hemisulfate | 2-Cyanopyrimidine | Esomeprazole | Aloxistatin | E-64 |
Related Compound Libraries | Bioactive Compound Library | Protease Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
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$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |