Product Details
Product Name:
KCC-07 |
CAS No.:
315702-75-1 |
Purity:
99.01% |
Supply Ability:
10g |
Release date:
2024/11/17 |
Product Introduction
Bioactivity
名稱 | KCC-07 |
描述 | KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. |
細(xì)胞實(shí)驗(yàn) | KCC-07?treatment?Medulloblastomas (MB) cells, Concentration with?10 μM and?Incubation Time with?72 hours |
體外活性 | In vitro, KCC-07 treatment Medulloblastomas (MB) cells?clearly inhibited MB cell growth, consistent with induction of anti-proliferative BAI1/p53/p21 signaling |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 22.5 mg/mL (83.54 mM)
|
關(guān)鍵字 | KCC07 | BAI1 | p53 | inhibit | ADGRB1 | anticancer | Inhibitor | DNA Alkylator/Crosslinker | MBD2 | anti-proliferative | ADGR | KCC-07 | KCC 07 | brain-penetrant |
相關(guān)產(chǎn)品 | Cyclophosphamide hydrate | Lomustine | Bendamustine hydrochloride | Busulfan | N-Nitroso-N-methylurea | Ifosfamide | Oxaliplatin | Streptozocin | Temozolomide | Cyclophosphamide | Carboplatin | Cisplatin |
相關(guān)庫 | 抗肺癌化合物庫 | 酪氨酸激酶分子庫 | 毒性化合物庫 | 血腦屏障通透化合物庫 | 抑制劑庫 | 干細(xì)胞分化化合物庫 | NO PAINS 化合物庫 | 抗衰老化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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