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Postion:Product Catalog >JW 67
JW 67
  • JW 67

JW 67 NEW

Price $38 $54 $89
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: JW 67 CAS No.: 442644-28-2
Purity: 97.02% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameJW 67
DescriptionJW 67 is an inhibitor of canonical Wnt pathway signaling. JW 67 rapidly reduced active β-catenin with a subsequent downregulation of Wnt target genes, including AXIN2, SP5, and NKD1.
In vitroJW 67 inhibits the canonical?Wnt?signaling with an?IC50?of 1.17μM[1]. JW 67 (1 μM) increased concentration of AXIN2 and decreased the active form of β-catenin[1]. JW 67 (10 or 25μM) reduced growth of SW480 CRC cells in vitro by inhibiting cell-cycle progression at the G1/S[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (152.14 mM)
Keywordsinhibit | JW 67 | Wnt | Inhibitor | CK1 | complex | JW-67 | β-catenin | GSK-3b | JW67 | AXIN | multiprotein | APC
Inhibitors RelatedUrea | PRI-724 | Wnt pathway activator 1 | L-quebrachitol | MSAB | EMT inhibitor-1 | Wogonin | CHIR-99021 | XAV-939 | Nefopam hydrochloride | KY-05009 | Bisdemethoxycurcumin
Related Compound LibrariesBioactive Compound Library | Neuroprotective Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Stem Cell Differentiation Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library | Neuronal Differentiation Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$2800.00/100mg
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TargetMol Chemicals Inc.
2024-10-23
$0.00/10mg
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ShenZhen H&D Pharmaceutical Technology Co., LTD
2024-06-05
$166.00/1mg
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TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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