Isoguvacine hydrochloride NEW
| Price | $34 | $58 | $88 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Isoguvacine hydrochloride | CAS No.: 68547-97-7 |
| Purity: 99.41% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Isoguvacine hydrochloride |
| 描述 | Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2S, α5β2γ2S, and ρ1 subunit GABAA receptors. |
| 體外活性 | Treatment of 50 μM Isoguvacine to block epileptiform events in 2 of 6 organotypic hippocampal slice cultures, Isoguvacine dose-dependently inhibits hypomagnesium-induced epileptiform events[2]. Isoguvacine binds to mouse forebrain synaptic membrane preparations and can specifically bind to GABA, muscimol and bicuculline, but not picrotoxin or diaminobutyric acid. The highest levels of binding are observed in the cerebellum, cortex and hippocampus[3]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 90 mg/mL (550.12 mM) DMSO : 20 mg/mL (122.25 mM), Sonication is recommended. |
| 關(guān)鍵字 | γ-Aminobutyric acid Receptor | Isoguvacine | GABA Receptor | Gamma-aminobutyric acid Receptor | Isoguvacine Hydrochloride | Isoguvacine hydrochloride | inhibit | Inhibitor |
| 相關(guān)產(chǎn)品 | Valproic acid sodium salt | Penicillin G sodium salt |
| 相關(guān)庫(kù) | 疼痛相關(guān)化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 神經(jīng)退行性疾病化合物庫(kù) | 膜蛋白靶向化合物庫(kù) | 神經(jīng)保護(hù)化合物庫(kù) | 已知活性化合物庫(kù) | 離子通道庫(kù) | 古代經(jīng)典名方目錄分子庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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