Product Details
| Product Name:
Ipsalazide |
CAS No.:
82101-17-5 |
| Purity:
99.43% |
Supply Ability:
10g |
| Release date:
2024/11/20 |
Product Introduction
Bioactivity
| Name | Ipsalazide |
| Description | Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease. |
| In vitro | Ipsalazide is designed with the replacement of the sulfapyridine of sulfasalazine by carrier molecules, aiming to mitigate side effects. Sulfasalazine exerts beneficial effects in colitis by releasing 5-aminosalicylic acid in the colon, but its use can be limited by side effects[1]. |
| In vivo | Within 7 days of a single oral dose of ipsalazide (4 g/kg in mice or 2 g/kg in rats), no deaths or visible abnormalities occurred. At postmortem, no abnormalities were observed. The carrier molecule of ipsalazide (ABG) is readily absorbed, with nearly half of the dose appearing in the urine. However, approximately 40% of the ABG was not recovered, and it is possible that this has undergone further metabolism, resulting in the loss of the aromatic amine function, which is the basis for the colorimetric measurement of ABG[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Ipsalazide |
| Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Anhui Ruihan Technology Co., Ltd
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