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Postion:Product Catalog >API>Antipyretic analgesics>Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)>Indometacin
Indometacin
  • Indometacin
  • Indometacin
  • Indometacin
  • Indometacin
  • Indometacin

Indometacin NEW

Price Get Latest Price
Package 1Kg/Bag 25Kg/Bag 100Kg/Bag
Min. Order: 1Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-12-23

Product Details

Product Name: Indometacin CAS No.: 53-86-1
EC-No.: 200-186-5 Min. Order: 1Kg/Bag
Purity: 0.99 Supply Ability: 20 tons
Release date: 2024/12/23

Product Information 



Product name

Valsartan

CAS No.

137862-53-4

Molecular Formula

C24H29N5O3

Molecular Weight

435.519

Quality Standard

98% up, USP/JP/EP

Appearance

White to almost white powder



COA of Valsartan 



ITEMS

STANDARDS

RESULTS

Appearance

White to almost white powder

White powder



Identification

Infrared absorption:

The IR spectrum is consistent with that obtained with the reference


Conforms

The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay

Conforms

Absorbance

NMT 0.02

0.003

Water

NMT2.0%

0.56%

Residue on ignition

NMT0.1%

0.06%

Heavy metals

NMT0.001%


Related compounds

(HPLC)

Compound A NMT1.0%

0.49%

Compound B NMT0.2%

0.08%

Compound C NMT0.1%

Undetected

Any other individual impurity NMT0.1% (excluding compound A )

0.04%

Total impurities NMT0.3% (excluding compound A )

0.20%

Residual solvents(GC)

Ethyl acetate NMT5000ppm

2820ppm

Dichloromethane NMT600ppm

Undetected

Methanol NMT3000ppm

Undetected

N,N-Dimethylformamide NMT880ppm

Undetected

Assay

98.0—102.0%

99.2%

Conclusion

The analysis results show that this batch of valsartan conforms to USP


Usage 


Function of Valsartan

Valsartan is an angiotensin II receptor antagonist anti-hypertensive drug. The drug can block the type I (AT1) receptor of angiotensin II, increase the plasma level of angiotensin II and stimulate The unblocked AT2 receptor also counteracts the role of the AT1 receptor, so as to achieve the effect of dilating blood vessels and lowering blood pressure, the effect is lasting and stable, and the toxic and side effects are small. Therefore, valsartan is mainly suitable for antihypertensive, mild to moderate primary hypertension, especially for the treatment of secondary hypertension caused by kidney damage.


Company Information 

Article illustration





Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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