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Postion:Product Catalog >API>Antineoplastic agents>Tinib Antineoplastic drugs> Imatinib Mesylate (STI571)
 Imatinib Mesylate (STI571)
  •  Imatinib Mesylate (STI571)

Imatinib Mesylate (STI571) NEW

Price Get Latest Price
Package 1g
Min. Order: 1g
Supply Ability: 1kg
Update Time: 2024-03-12

Product Details

Product Name: Imatinib Mesylate (STI571) CAS No.: 220127-57-1
Min. Order: 1g Purity: 98% HPLC
Supply Ability: 1kg Release date: 2024/03/12

Imatinib mesylate is the mesylate salt of imatinib, a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to intracellular pockets located within tyrosine kinases (TKs), thereby inhibiting ATP binding and preventing phosphorylation and subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene and receptor TK encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Inhibition of bcr-abl TK leads to decreased malignant cell proliferation and increased apoptosis in Philadelphia-positive (Ph+) hematological malignancies such as CML and ALL; effects on c-kit TK activity inhibit hypertrophy in diseases overexpressing c-kit Cells and cell proliferation, such as in mastocytosis and gastrointestinal stromal tumors (GIST).

Company Profile Introduction

Shandong Perfect Biotechnology Co.Ltd founded in 2014, the company is a supplier and service provider of pharmaceutical and chemical raw materials and animal husbandry and animal health industries. The company is located in Jinan, a beautiful spring city, where the transportation is developed, the logistics is convenient, and the industrial supporting resources are abundant, which provides a stable foundation for the promotion of the company's products. In 2018, the company initiated the establishment of Shandong Qinshi Biotechnology Co., Ltd. to serve domestic veterinary drug preparation companies, and Qinshi successfully passed the national veterinary drug GSP certification on September 10, 2018. In 2020, the company passed the ISO quality management system certification. As a result, the company has formed a pattern in which Jihao Company exports pharmaceutical and chemical raw materials and intermediates, and Qinshi Company serves domestic animal protection enterprises as veterinary raw materials. In this way, it can be more stable and standardized to meet the needs of different customers at home and abroad. At present, the company cooperates closely with several university research institutes and high-tech pharmaceutical industry companies, strictly controls each link from product research and development, production, sales, and dares to innovate, and continuously improves product quality and competitive advantages to promote the company's benign and stable development. We continue to develop superior varieties with our partners, and provide customers with products that meet customer requirements in accordance with CP, JP, BP, USP, EP and other standards, making our products and services a close and stable partner for customers. The company pays equal attention to the development of both international and domestic markets, and a complete sales team can serve its partners wholeheartedly. We provide products and services to our customer

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  • Since: 2014-09-09
  • Address: No.28 Hua Long Road,Ji Nan City,China
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