IL-4-inhibitor-1 NEW
| Price | $39 | $185 | $347 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: IL-4-inhibitor-1 | CAS No.: 1332184-63-0 |
| Purity: 98.26% | Supply Ability: 10g |
| Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名稱 | IL-4-inhibitor-1 |
| 描述 | IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway. |
| 體外活性 | IL-4-inhibitor-1 exhibits functional disruption of type II IL-4 binding in a cellular context and dose-dependent reduces pSTAT-6 levels (EC50 = 3.1 μM)[1]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 10 mg/mL DMF : 27.0 mg/mL (84.1 mM) DMSO:PBS (pH 7.2) (1:5) : 0.1 mg/mL DMSO : 50 mg/mL (155.61 mM), Sonication is recommended. |
| 關鍵字 | IL4inhibitor1 | IL-4-inhibitor-1 | IL 4 inhibitor 1 |
| 相關產品 | Inosine pranobex | Apilimod mesylate | Amlexanox | Isosteviol | Dexamethasone acetate | L-Arginine | Bergenin | α-Terpineol | Dexamethasone | Diallyl disulfide | Linalool | Apilimod |
| 相關庫 | 經典已知活性庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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