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Postion:Product Catalog >IL-18 Protein, Mouse, Recombinant (His)
IL-18 Protein, Mouse, Recombinant (His)
  • IL-18 Protein, Mouse, Recombinant (His)

IL-18 Protein, Mouse, Recombinant (His) NEW

Price $2730
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-01

Product Details

Product Name: IL-18 Protein, Mouse, Recombinant (His) Purity: Greater than 95% as determined by reducing SDS-PAGE
Supply Ability: 10g Release date: 2024/11/01

Product Introduction

Bioactivity

名稱IL-18 Protein, Mouse, Recombinant (His)
描述Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins and virally encoded IL-18BP homologs. It augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. In the presence of IL-12 or IL-15, IL-18 enhances anti-viral Th1 immune responses by inducing IFN-gamma production and the cytolytic activity of CD8+ T cells and NK cells. In the absence of IL-12 or IL-15, however, IL-18 promotes production of the Th2 cytokines IL-4 and IL-13 by CD4+ T cells and basophils.
存儲條件store at low temperature | Shipping with blue ice.

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$2300.00/1mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-22
$2730.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-10-23
$0.10/1kg
VIP2Y
Zibo Hangyu Biotechnology Development Co., Ltd
2024-01-12
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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