IDO5L NEW
| Price | $43 | $78 | $126 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: IDO5L | CAS No.: 914471-09-3 |
| Purity: 99.75% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | IDO5L |
| 描述 | IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). |
| 體外活性 | In an immunologically active mouse model, INCB024360 effectively inhibited tumor growth. Similarly, in mice bearing GM-CSF-secreting B16 tumors, INCB024360 (75 mg/kg b.i.d) demonstrated dose-dependent tumor growth suppression. |
| 體內(nèi)活性 | INCB024360 significantly inhibits IDO1 in HeLa cells (IC50 = 19 nM) and promotes differentiation in CD4+ T cells, CD8+ T cells, and NK cells. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 27.2 mg/mL (100 mM) DMSO : ＜1 mg/mL (insoluble or slightly soluble), Sonication is recommended. |
| 關(guān)鍵字 | INCB-14943 | Inhibitor | inhibit | INCB 14943 | IDO-5L | Indoleamine 2,3-Dioxygenase (IDO) | IDO5L |
| 相關(guān)產(chǎn)品 | Palmatine chloride | GNF-PF-3777 | Coptisine chloride | Necrostatin-1 | IDO-IN-7 | IDO1-IN-1 | Indoximod | Palmatine | IDO inhibitor 1 | Epacadostat | β-Lapachone | IDO-IN-12 |
| 相關(guān)庫 | 表型篩選靶點鑒定庫 | 經(jīng)典已知活性庫 | ReFRAME 相關(guān)化合物庫 | 抗癌細(xì)胞代謝庫 | 抑制劑庫 | NO PAINS 化合物庫 | 代謝化合物庫 | 已知活性化合物庫 | 含氟化合物庫 | 抗代謝疾病化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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