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Postion:Product Catalog >HX 531
HX 531
  • HX 531

HX 531 NEW

Price $39 $68 $122
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: HX 531 CAS No.: 188844-34-0
Purity: 99.43% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

NameHX 531
DescriptionHX 531 is a RXR antagonist (IC50 of 18 nM). HX 531 prevents HF diet-induced obesity, insulin resistance, and diabetes by reducing tissue TG content in white adipose tissue (WAT), skeletal muscle, and liver in mice.
In vivoMETHODS: HX531 (100 mg/kg, oral) was administered to mice, and the maximum plasma concentration (Cmax), time required to reach maximum concentration (Tmax), area under the plasma concentration-time curve (AUC), and elimination half-life (t1/2) were measured by HPLC and gas chromatography. RESULTS In mice, they were 4.1 μg/mL, 1.5 hours, 19.3 μg h/mL, and 1.9 hours, respectively. [2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 3 mg/mL (6.20 mM)
KeywordsRetinoic acid receptors | inhibit | RAR/RXR | HX531 | HX-531 | Inhibitor | HX 531 | Retinoid X receptors
Inhibitors RelatedIsotretinoin | Oxybenzone | MSU-42011 | Tazarotene | Etodolac | KCL-286 | ER 50891 | Acitretin | Tamibarotene | Bexarotene | TTNPB | K-8012
Related Compound Libraries核受體化合物庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 代謝化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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